Growth hormone (GH) plays a crucial role in growth, metabolism, and overall health. Its levels and effects change significantly as we age.  Growth hormone peaks during puberty and remains stable throughout early adulthood. Beginning around the age of 30, growth hormone levels begin to gradually decline. 

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Effects of Decreased GH with Aging

1. Muscle Mass and Strength: Lower GH levels contribute to sarcopenia (age-related muscle loss), leading to decreased strength and mobility.
2. Body Fat: GH helps regulate metabolism and fat distribution. Reduced GH levels can result in increased abdominal fat and changes in fat distribution.
3. Bone Density: GH plays a role in bone health. Lower levels can contribute to decreased bone density and an increased risk of osteoporosis and fractures.
4. Skin and Hair: GH affects skin elasticity and thickness. Reduced levels can contribute to the thinning of the skin and the appearance of wrinkles.
5. Energy and Vitality: Lower GH levels can impact overall energy levels, mood, and cognitive function.

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Ways to naturally support growth hormone levels include proper nutrition, strength training and high intensity exercise, consistent restorative sleep and stress management.  

Sermorelin is a synthetic peptide that mimics the action of growth hormone-releasing hormone (GHRH), which stimulates the pituitary gland to produce and release more growth hormone. A peptide is a short chain of amino acids that can act as signaling molecules that help regulate various biological processes, including growth, metabolism, and cell signaling.  Sermorelin, through raising growth hormone levels, may support increased muscle mass, reduced body fat, and improved sleep and energy levels in adults. 

Unlike direct growth hormone injections, sermorelin works by stimulating the body’s natural hormone production, which means a lower risk of side effects and complications that are associated with direct growth hormone supplementation.  

Sermorelin is available by prescription through compounding pharmacies.  It is a daily subcutaneous injection given in the evenings since growth hormone peaks during sleep.  It is well tolerated and has minimal side effects such as mild dizziness and headache that improve over time.